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The world will know what is dandruff

November 7 2007

An international group of scientists decipher the genetic code of the fungus that causes dandruff. Experts hope that a detailed understanding of the genome of the fungus Malassezia globosa will help develop more effective methods of getting rid of dandruff.

It is considered that dandruff suffers half the world population. And men dandruff occurs more frequently than women. According to statistics, on the human head, on average live about 10 million Malassezia globosa.

Yeast-like fungus feeds on the so-called cutaneous sebum, or sebum. That is why dandruff is usually first appears in adolescents, when the sebaceous glands begin to work at full strength.

Gland secretion protects the skin from drying and damage. The fungus is not able itself to produce fatty acids, therefore, depends on the skin sebum. The genome of Malassezia globosa is 300 times smaller than human, and consists of only 4,285 genes.

The latest research shows that the fungus produces lipase - an enzyme, which causes dandruff. First fungi using lipase to overcome layer secretion of the sebaceous glands, and then penetrate the outer layer of skin and lead to an acceleration of the natural process of cell renewal of the scalp, and therefore - and dandruff, reports

Scientists have found that the fungus produces eight species of lipase, as well as three types of phospholipase. It is in effect on these proteins, the enzymes may be hiding secret to successful treatment of dandruff.

The fact that Malassezia globosa was the cause of dandruff, it was discovered only five years ago. To decipher its genome, scientists have grown ten liters of mold and froze it in liquid nitrogen. Then they removed the DNA and break it down into tiny components.

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