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Memory improves the genetic mutation

April 9 2007

Canadian scientists have discovered a genetic mutation that improves the long-term memory.

Researchers believe that this discovery could lead to the creation of new drugs to treat the symptoms of Alzheimer's disease and other neurodegenerative diseases. In experiments with mice, the specialists of the University of Montreal found that rodents that have defective version of the gene encoding a fusion protein called eIF2a, better lend themselves to training and perform tasks faster.

In particular, the mutant mice running in the pool, much faster learning is under the water a small platform, which enables them to stand on its feet. Lead researcher Mauro Costa-Mattioli said that mice with a mutant gene differed from their counterparts in much the same as the person who is able to learn by heart a page of text after the first reading is different from ordinary people.

To prove that the unusual ability of mice effectively connected with a mutation of the gene eIF2a, scientists have artificially increased the levels of this protein in animals, then they are showing clear signs of memory disorders. According to Mattioli, drugs that can block the action of protein eIF2a in the human body, can be of great benefit to patients suffering from memory loss, in particular, patients with Alzheimer's disease.

Scientists believe: "We may not be able to cure them in such a way, but we hope we will reimburse the memory deficit that occurs when such diseases. Magazine reports Cell.

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