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The Japanese have cured paralysis in mice with stem cells

February 4 2009

Japanese scientists for the first time in the world failed to cure mice with paralyzed limbs using stem cells.

Scientists led by Professor Hideyuki Okano iPS-cultured cells from human skin cells. Then from it were grown cells that form neural tissue. The cells were transplanted to 29 mice with paralyzed lower legs due to spinal cord injuries. Cured mice a month after the operation began to go, and some even run.

"Our research has not been as such aims to achieve irrefutable evidence of the therapeutic effect of human iPS-cell. Nevertheless, the results were just such evidence. There are still issues related to the risk of tumor (after treatment), but at least , we have taken the first step, "- said Prof. Okano.

Induced pluripotent stem cells are of great interest for possible treatment of severe spinal cord injury, neurodegenerative diseases, particularly Parkinson's disease and Alzheimer's. They can be used in the treatment of hereditary diseases. However, the use of stem cells associated with the risk of developing cancer because they are able to uncontrolled proliferation, reports RIA Novosti .

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